EFFECTS OF HETEROGENEITY ON THE ECOLOGICAL DIVERSITY AND REDUNDANCY OF FOREST FAUNA


Integrating Conformational Dynamics and Perturbation-Based Network Modeling for Mutational Profiling of Binding and Allostery in the SARS-CoV-2 Spike Variant Complexes with Antibodies: Balancing Local and Global Determinants of Mutational Escape Mechanisms

In this study, we combined all-atom MD simulations, the ensemble-based mutational scanning of protein stability and binding, and perturbation-based network profiling of allosteric interactions in the SARS-CoV-2 spike complexes with a panel of cross-reactive and ultra-potent single antibodies (B1-182.1 and A23-58.1) as well as antibody combinations

read more

On the master space for brane brick models

Abstract We systematically study the master space of brane brick models that transpharm online shopping represent a large class of 2d (0, 2) quiver gauge theories.These 2d (0, 2) theories are worldvolume theories of D1-branes that probe singular toric Calabi-Yau 4-folds.The master space is the freely generated space of chiral fields subject to the

read more

Tonic exploration governs both flexibility and lapses.

In many cognitive tasks, lapses (spontaneous errors) are tacitly dismissed as the result of nuisance processes like sensorimotor noise, fatigue, or disengagement.However, some lapses could also be caused by exploratory noise: randomness in behavior that facilitates learning in changing environments.If so, then strategic processes would need only up

read more